woman sitting up in bed with insomnia

Which is the Best Vape for Sleep: Melatonin or CBD?

A good night’s sleep is crucial for physical and mental health. If you’ve been having trouble getting enough zzz’s, you might be searching the supplement aisle. Vaping products are very popular, with options for keeping you awake and helping you fall asleep. After a few puffs, you are relaxed and on your way to sweet dreams. With all the choices, you might ask yourself: what is the best vape for sleep?

There are two types of vapes for sleep — ones that use melatonin and ones that use CBD. They both help you fall asleep faster and stay asleep longer, but there are significant differences between the two products. We will closely examine some of each type to help you rest easy with your decision.

Best Melatonin Vape for Sleep

bright blue vapor or wavy smoke on white background

Melatonin is a natural sleep aid used by many who have trouble falling asleep. Melatonin supplements are available in pill, spray, cream, gummy, liquid, or vape form.

Melatonin helps to regulate your body’s internal clock or circadian rhythm, and your body naturally produces melatonin when the brain perceives darkness. If you use electronics, work the night shift, experience jet lag, or have a busy lifestyle, your body might need help getting back on track.

Oral melatonin, such as liquids or vapes, offer the fastest-acting way to absorb melatonin into your bloodstream instantly. Oral melatonin has a bioavailability of 98% and can be absorbed in as little as 1-4 minutes (it may take longer to feel the effects). Plus, melatonin supplements, in general, won’t cause drowsiness.


MELO Plus Melatonin Diffuser is a simple blend of natural melatonin, organic vegetable glycerin, and a tropical blend of hand picked berries and melon. Five to ten inhales are all you need as you settle down for the night.

Ten puffs equal 1.3 milligrams of melatonin, but most people find a dose of less than .5 milligrams (or two to three puffs) is effective in getting them to sleep. A MELO Plus Diffuser has 800 puffs, twice that of the MELO Air. That means one diffuser lasts quite a while.


MELO Air has ten different flavor options to deliver a gentle approach to sleep. It is free from THC, CBD, vitamin E acetate, and other additives or preservatives. Just three simple ingredients — natural melatonin, organic vegetable glycerin, and essential oils — ensure no unnecessary or harmful additives enter your body.

Plus, there is nothing to harm your lungs. A few simple breaths of the vapor are enough to go directly where your body knows how to use them. Instead of inhaling, you are breathing the vapors through your nose. Unlike traditional vape pens, the mixture's temperature is kept low to preserve the melatonin and essential oils.

Cloudy Melatonin Diffuser

Cloudy is similar to the MELO Plus and MELO Air, with concentrated melatonin, lavender, and chamomile as the three basic ingredients. But they also add l-theanine, propylene glycol, and vegetable glycerin.

Propylene glycol is a food additive that helps maintain consistency, moisture, and texture. It is considered safe. L-theanine is an amino acid that may help ease anxiety and stress and contribute to reduced insomnia. Like all MELO products, they are 100% free of controlled substances, vegan, and cruelty-free.

Best CBD Vape for Sleep

young man sleeping while lying down on the glass

CBD may have anti-anxiety and calming effects for many users. It’s used for an incredibly wide variety of products: there are CBD oils, creams, sprays, and vapes, among dozens of others.

While it doesn’t exactly cause drowsiness, CBD has properties that can help put your body into a state of relaxation, and that can lead to better sleep.

It’s important to note that THC is the chemical in cannabis plants that gets people “high,” and CBD is the plant’s second most abundant compound. Any product labeled as CBD can have up to .3% THC, but that is generally not enough to produce a “high.”

While CBD products are plant-based, the compound needs to be extracted from the plant. It is then mixed with a carrier oil to create CBD oils and other products.

When researching CBD products, check to see whether the CBD is made from organic hemp plants. Chemicals and pesticides permeate non-organic products and may have health risks.

Check for clues about how much processing was used to create the product. Look for the term “full spectrum” on the label, for example, as those products will also contain beneficial compounds such as fatty acids, flavonoids, terpenes, essential vitamins and minerals, plant fibers, and chlorophyll along with CBD. They may also contain trace amounts of THC.

The other two options are “broad-spectrum,” which does not contain THC but may also include some other plant components, and CBD isolate, which only contains CBD. While a few CBD vape pens are specifically geared toward sleep, most concentrate more generally on relaxing properties.

3Chi CBD Vape Cartridge - Sleep

3Chi Sleep Broad Spectrum CBD Cartridge is a blend of pure full spectrum oil with no cutting agents. It contains up to 90-95% total cannabinoid, 5-10% terpenes, and less than .3% THC (which is typically non-detectable).

It has a clean hemp taste without additives such as vitamin E. A serving size is one 6-second puff. The number of servings in a cartridge depends on how long you wait between inhales and the length of the inhale.

Unlike MELO Air diffusers, CBD vapes work by inhaling the warmed substance into your lungs. The cartridge is battery-powered to heat up liquids, releasing the compounds that make it effective. Testers of 3Chi reported improved sleep without morning grogginess.

Medix CBD

Medix CBD Vape for Sleep contains pure full-spectrum CBD and complete terpene formulas. If you head to their website, you can see lab results detailing the active ingredients. The formula produces a relaxed state which should help you fall asleep.

A serving size is one drag (or pull), and you’ll get 2.5 mg of CBD in each. Each disposable cartridge provides approximately 200 hits. An automatic battery kicks in when it senses you are inhaling.

CBDSocial Sleep Vape Cartridge

Combining CBN, full-spectrum CBD, and CBD Isolate can help support a restful night’s sleep. You will wake up in the morning without feeling groggy. The flavor is natural; there are no flavor additives.

CBDSocial Sleep Vape comes in 500 mg and 1000 mg pens. (The average size cartridge is 500 mg, so the larger size will last twice as long.) Products are pesticide-free, lab-tested, use CO2 extraction, and are made in the USA from industrial hemp.

Melatonin vs. CBD Vape Pens

While both melatonin and CBD vape pens will help you get to sleep, there are significant differences between the two products. Melatonin is produced naturally by your body, and thus your body knows what to do with it.

CBD is plant-derived, but works with receptors in your body to produce the desired effect. In this way, it acts more like a drug or supplement. Melatonin is the more natural choice.

While the amount of THC is regulated, there is still a remote possibility that it could appear on drug tests. If your job frowns on this substance, you might not want to take any chances with full- or broad-spectrum products.

While CBD is generally recognized as safe, everyone’s body reacts differently. With both CBD and melatonin, start with the lowest dose and see how it works. You may try other brands or formulations if one does not work for you.

Choose MELO Plus or MELO Air for a Natural Vape

Many factors can cause sleep issues, including mental health disorders, environmental factors, medications, and physical ailments. The key to long-lasting sleep is spending time addressing these issues, but you can’t do that unless you are well-rested.

When shopping for a safe, effective, healthy oral supplement to help you relax and get a good night's sleep, look no further than MELO. A MELO Plus or MELO Air vape can help you get much-needed rest with a few inhales as you settle down on your pillow.

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